Hollyhock did give Bojack another chance after accepting that it was his mother who drugged her. Yes she threw out his pills out of paranoia when she visited him but she apologised and intended to maintain some kind of relationship. It was when she met Pete Repeat and found out about Prom and him almost sleeping with Penny that she decided to distance herself from him. Bojack then turning up at her uni to lecture was too much for her and, frankly, she should’ve told him that she wanted nothing to do with him rather than simply avoiding him because it just led to him causing her more discomfort by trying to get close. But yeah, when it comes to Hollyhock I think it was a lot more to do with her finding out even more sus stuff about him than just the pill sitch