I’ve seen people talk about actors and artists that had a terrible time.
My own would be Anne Rice. She wrote Interview with the Vampire after her young daughter died of Leukemia. Then her husband suddenly died of a brain hemorrhage. I suspect her Christian, anti-fanfic phase was a result of mental illness and manipulation from the publishers, although I don’t think she ever apologized.
Ned Vizzini. Wrote It’s Kind of a Funny Story, which was inspired by his own struggle with depression/suicidal thoughts and then he ended up taking his life a few years ago. Pretty upsetting because that book helped me a lot in high school.