I’ve seen people talk about actors and artists that had a terrible time.
My own would be Anne Rice. She wrote Interview with the Vampire after her young daughter died of Leukemia. Then her husband suddenly died of a brain hemorrhage. I suspect her Christian, anti-fanfic phase was a result of mental illness and manipulation from the publishers, although I don’t think she ever apologized.
Isabel Falls, who is transgender, wrote an excellent science fiction story “I sexually identify as an attack helicopter gunship,” which was published in Clarkesworld Magazine.
She was then attacked by a number of twitter mob led by left wing authors such NK Jemisin for supposedly being a 4chan plant, and ended up taking the story down and disappearing from the internet.
Oh, and most of the people attacking her admitted they’d never read the story, they just assumed it was a 4chan op.
I think she also changed her name and/or socially detransitioned. She didn’t feel she could safely live as Isabel after all the bad press.
I didn’t know about NK Jemisin’s involvement, but I’ve lost some respect for her now.