I’ve seen people talk about actors and artists that had a terrible time.
My own would be Anne Rice. She wrote Interview with the Vampire after her young daughter died of Leukemia. Then her husband suddenly died of a brain hemorrhage. I suspect her Christian, anti-fanfic phase was a result of mental illness and manipulation from the publishers, although I don’t think she ever apologized.
I think it is difficult for people to understand who do not have mental issues. I have in certain situations severe anxiety. People even those who know me well often do not understand that I cannot just help being the way I am. That the feelings that come are not something I can control. People constantly interpret my behaviour as asocial and unfriendly but I am far from that I just cannot help becoming defensive and silent when I am afraid.