I took a very wonderful class in college where we read Moby-Dick and Uncle Tom’s Cabin in dialogue with each other, and it was perfect. They came out at essentially the same moment but are incredibly different in their tone, goals, and impact. They’re essentially part of two unrelated literary traditions, from two very different authors, and reading then side-by-side and looking at their overlaps and differences is a great way of exploring topics from the period.

His book The Abominable is very much this as well, about a crew of alpinists ascending Mt. Everest.

Lawrence Buell has a book about the concept of the Great American Novel that heavily incorporates both Blood Meridian and Beloved. BM is definitely already a part of the modern canon.

Didn’t see anyone else mention it so I’ll say Rosemary’s Baby. The novel is almost too slow a burn, and just ends up being sort of a boring slice of life novel sprinkled with the occasional “Oooh, ominous!” moment, whereas the movie condensed those moments into a more pervasive atmosphere of dread.