Watch Big Mouth. It doesn’t go into substance abuse much, but it has quite profound mental health and philosophical metaphors/themes among lots of hilarious crude humor and comic discomfort. Very relatable for teens and young adults.

Also, the spin-off, Human Resources, is absolutely gold. It’s less absurd and more cerebral. Heavily works with the concept of addiction, but in a way that the main characters are personified emotional fragments of the human’s minds. I.e Logic is battling to help Emotion see that her abusive boyfriend, Addiction, is a POS.

I will say there are some dark moments where relapse is implied. What makes this show unique is that they keep some absurdity with it even during gut-wrenching moments (some were very moving as a recovered addict).

The way they portray the fear and isolation and desperation… the show is certainly underrated.