I’ve seen people talk about actors and artists that had a terrible time.
My own would be Anne Rice. She wrote Interview with the Vampire after her young daughter died of Leukemia. Then her husband suddenly died of a brain hemorrhage. I suspect her Christian, anti-fanfic phase was a result of mental illness and manipulation from the publishers, although I don’t think she ever apologized.
I just read Although Of Course You End Up Becoming Yourself. To think that he died because he had finally, after like twenty years on the same antidepressant which gave him terrible side effects, thought that was in such a great positive life place that he could try transitioning off the antidepressants, only to find that he did in fact need said antidepressants and no other treatment would work, only to find that even going back onto the same antidepressants would no longer work, trying anything to fix it again for a year before dying by suicide…. It’s so so sad.