I’ve seen people talk about actors and artists that had a terrible time.
My own would be Anne Rice. She wrote Interview with the Vampire after her young daughter died of Leukemia. Then her husband suddenly died of a brain hemorrhage. I suspect her Christian, anti-fanfic phase was a result of mental illness and manipulation from the publishers, although I don’t think she ever apologized.
Dave Barry has mad me sob laughing with the silliest shit, but whenever he writes about infidelity, that shit suddenly gets very real very fast. Don’t know anything about his personal life, but I know how eerily powerfully he writes about men finding out their wives have cheated on them.