When Bojack finally gave MPB his crossover episode

Sabrina is a female human likely weighing no more than 120 lbs. Bojack is a male horse likely weighing somewhere in the ballpark of 800-1200 lbs. Men tend to tolerate alcohol and other substances better than women, but the bigger the organism, the more blood volume they have, meaning the more substances they can consume and tolerate without incident.

Why is PB driving on the right side in the Pickles slide